Vaginal Progesterone, Revisited: What the New AJOG Meta-analysis Really Shows

A new individual-patient data meta-analysis cuts through years of controversy and confirms that vaginal progesterone prevents preterm birth in women with a short cervix.

The question of whether vaginal progesterone prevents preterm birth has carried more noise than clarity in recent years. Between PROLONG, shifting guidelines, and widespread clinician uncertainty, many pregnant women with a short cervix have been caught in the middle. The new Research Letter in the American Journal of Obstetrics & Gynecology provides th…