ObGyn Intelligence

ObGyn Intelligence

The Evidence Room: Depo-Provera, Meningiomas, and Professional Responsibility

The delicate balance of truth and tranquility: providing women with undiluted facts, framed by compassion, understanding and reassurance.

Amos Grünebaum, MD's avatar
Amos Grünebaum, MD
Oct 15, 2025
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What is Depo-Provera?

Depo-Provera is a contraceptive injection given every three months. It contains depot medroxyprogesterone acetate (dMPA), a synthetic progestin that suppresses ovulation. Approved in the United States in 1992, it is used by about 2% of American women aged 15 to 49 and nearly 68 million women worldwide. For many, its convenience—no d…

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