Evidence-Based Medicine: Folic Acid, 5-MTHF, and the MTHFR Gene: What Pregnant Women (and Doctors) Should Know

And why the critics of 5-MTHF are missing the forest for the trees

Neural tube defects (NTDs) are serious birth defects of the brain and spine, including spina bifida and anencephaly. In the early 1990s, scientists discovered that daily folic acid before and during pregnancy could cut the risk of NTDs dramatically. This led to routine supplementation and food fortification, which reduced NTD rates worldwide.

Folic acid …