ObGyn Intelligence

ObGyn Intelligence

Antibiotics in Pregnancy: Life-Saving When Needed, Harmful When Not

From Semmelweis to stewardship: why infection prevention still defines safe maternity care. The Safety Ledger — Notes on accountability, error, and what it really takes to keep patients safe.

Amos Grünebaum, MD's avatar
Amos Grünebaum, MD
Oct 29, 2025
∙ Paid

Antibiotics once conquered maternal infection. Today, their overuse risks undoing that victory. True safety in obstetrics means knowing when and when not to prescribe.

It’s easy to forget that a century ago, childbirth was often deadly. Before antibiotics and antiseptic technique, infection was the leading cause of maternal death. In the mid-1800s, Ignaz…

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