ObGyn Intelligence: The Evidence of Women’s Health

ObGyn Intelligence: The Evidence of Women’s Health

High-Risk Pregnancy Intelligence

A Cheap Pill Can Prevent Preeclampsia. Most Women at Risk Aren’t Taking It.

In 2017, a landmark trial called ASPRE showed that low-dose aspirin, started before 16 weeks of pregnancy, reduced the risk of preterm preeclampsia by 62% in high-risk women.

Amos Grünebaum, MD's avatar
Amos Grünebaum, MD
Feb 11, 2026
∙ Paid

Every year in the United States, about 1 in 25 pregnancies is complicated by preeclampsia. Worldwide, it kills more than 70,000 mothers and 500,000 babies annually. And yet we have something that actually helps prevent it — a pill that costs pennies, sits on every pharmacy shelf, and has stronger evidence behind it than most things in obstetrics.

That pi…

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